MASTER DEGREE

INFORMATION FOR
PERSPECTIVE STUDENT
Requirements
Transitional agreements
Offices
Time tables

MASTER COURSE

Curricula (Chemical Engineering or Material Science and Engineering)
Curricula (Biomedical Engineering)
Internship
Thesis
1ST YEAR-1ST SEMESTER
BIOCHEMISTRY
The main objective of the course is to study basic and most advanced aspects of Biochemistry. The course will: provide students with structural features of the most relevant macromolecules, including proteins, carbohydrates, lipids and nucleic acids, to understand macromolecule’s structure-function relationships. It will describe key principles of enzyme structure, kinetics, and regulation. It will illustrate the bases for the understanding of molecular mechanisms of cellular macromolecules. Molecular mechanisms of biological recognition will be illustrated.
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CELL AND MOLECULAR BIOLOGY
The aim of this course is to provide basic knowledges about how the cell is done and how works as well as understanding of some fundamental mechanisms regulating gene expression and in turn cell identity and fate. Moreover, the course will provide knowledges about the technologies of gene expression and transfer in vitro. The main topics are:
  • Fundamentals of working principles of eukaryotic cells.
  • Gene expression regulation.
  • Stemness and differentiation.
  • Introduction to methodologies to modify gene expression and transfer genetic material into cells.
  • Interaction of stem cells with matherials.
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BIOMECHANICS
With the aim of modeling some complex behaviors of cells and tissues in cases of coupling between mechanical and biochemical events occurring at different scale levels, the course furnishes the mathematical background and explicitly writes and (analytically and/or numerically) solves the PDEs needed to approach - in the framework of the continuum mechanics - some biomechanical problems of interest. Starting from finite deformations, hyperelastic, viscoelastic and poroelastic models will be presented and ad hoc integrated with balance of mass and fluid content for taking into account growth and remodeling, as well as for catching some relevant phenomena like adhesion and structural reorganization in cells. Applications will be finally illustrated to show the practical use of the proposed theories for describing selected cell dynamics, growth of tumors and prostheses optimization in cardio-thoracic surgery.
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SYSTEM ANALYSIS FOR BIOENGINEERING
By the end of the course, the student will be able to model and analyse biomolecular processes by means of linear dynamical system theory.
Topics to be covered include basic system concepts; equations describing continuous- and discrete-time linear systems; State-space models and block diagrams; Time domain analysis. Introduction to linear feedback control. Controllability and Observability. PID controllers. Introduction to the analysis of nonlinear systems. Equilibrium points and limit cycles. Models of biochemical reactions and gene regulatory networks. Models of transcriptional activation and repression via Hill functions.
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